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À¯Ä¡ÀÇ Ä¡¾Æ¿ì½ÄÁõ È®ÀÎÀ» À§ÇÑ Á¤·®Çü±¤ºÐ¼®(QLF) °Ë»ç¹ýÀÇ ¿ì½ÄŽÁö´É·Â Æò°¡

Assessment of the Caries Detection Ability of Quantitative Light-induced Fluorescence (QLF) in Primary Teeth in vitro

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Á¶°æÇö, °­Á¤¹Î, Á¤È¸ÀÎ, ÀÌžç, ¼ÛÁ¦¼±,
¼Ò¼Ó »ó¼¼Á¤º¸
Á¶°æÇö ( Cho Kyung-Hyun ) - Yonsei University College of Dentistry Department of Pediatric Dentistry
°­Á¤¹Î ( Kang Chung-Min ) - Yonsei University College of Dentistry Department of Pediatric Dentistry
Á¤È¸ÀΠ( Jung Hoi-In ) - Yonsei University College of Dentistry Department of Preventive Dentistry & Public Oral Health
ÀÌžç ( Lee Tae-Yang ) - Yonsei University College of Dentistry Department of Pediatric Dentistry
¼ÛÁ¦¼± ( Song Je-Seon ) - Yonsei University College of Dentistry Department of Pediatric Dentistry

Abstract

º» ¿¬±¸ÀÇ ¸ñÀûÀº À¯Ä¡ÀÇ Ä¡¾Æ¿ì½ÄÁõ °Ë»ç¸¦ À§ÇÑ Á¤·®Çü±¤ºÐ¼®(quantitative light-induced fluorescence, QLF) ±â¼úÀÇ À¯È¿¼ºÀ» Æò°¡ÇÏ°í, ¿ì½Äº´¼ÒÀÇ ºÎÇÇ¿Í QLF ºÐ¼®°á°ú »çÀÌÀÇ »ó°ü°ü°è¸¦ È®ÀÎÇÏ´Â °ÍÀÌ´Ù. Ä¡¾Æ¿ì½ÄÁõ °Ë»ç¸¦ À§ÇØ 53°³ÀÇ ±³ÇÕ¸é ¹× 72°³ÀÇ ÀÎÁ¢¸éÀ» Æ÷ÇÔÇÑ ÃÑ 125°³ÀÇ À¯±¸Ä¡ Ä¡¸éÀ» ÈÞ´ë¿ë QLF Àåºñ¸¦ ÀÌ¿ëÇØ Á¶»çÇÏ¿© À¯±¸Ä¡ÀÇ Ä¡¾Æ¿ì½ÄÁõÀ» È®ÀÎÇÏ¿´´Ù. ¶ÇÇÑ Ä¡¾Æ¿ì½ÄÁõÀ» ºÐ·ùÇÏ°í ¿ì½Äº´¼ÒÀÇ ºÎÇǸ¦ °è»êÇϱâ À§ÇØ micro-CT ¹æ»ç¼± °Ë»ç¸¦ ½ÃÇàÇÏ¿´´Ù. »ó´ëÀûÀ¸·Î ³·Àº ¼öÄ¡¸¦ º¸¿´´ø ÀÎÁ¢¸é ¿ì½Ä¿¡´ëÇÑ ¥ÄR average °á°ú¸¦ Á¦¿ÜÇϸé, QLF ºÐ¼®°á°ú´Â À¯Ä¡ÀÇ Ä¡¾Æ¿ì½ÄÁõ Áø´Ü¿¡ ´ëÇØ ÃæºÐÇÑ ¼öÁØÀÇ Á¤È®¼º°ú ½Å·Úµµ¸¦ º¸¿´´Ù(¹Î°¨µµ0.75 - 0.94, ƯÀ̵µ 0.82 - 0.95, AUROC 0.88 - 0.98). Spearman »ó°üºÐ¼® °á°ú¿¡¼­´Â ¥ÄF average ¹× QS-Index¿Í ¿ì½Äº´¼Ò ºÎÇÇ »çÀÌ¿¡ Åë°èÀûÀ¸·Î À¯ÀÇÇÑ ³ôÀº »ó°ü¼ºÀ» È®ÀÎÇÒ ¼ö ÀÖ¾ú´Ù(r = 0.805 - 0.832, p < 0.001). QLF ±â¼úÀ» ÀÌ¿ëÇÑ Ä¡¾Æ¿ì½ÄÁõ °Ë»ç´Â ¾î¸°ÀÌÀÇÄ¡¾Æ¿ì½ÄÁõ Áø´Ü¿¡ ÀÖ¾î ¹æ»ç¼± ³ëÃâ¿¡ ´ëÇÑ °ÆÁ¤ ¾øÀÌ ¾ÈÀüÇÏ°Ô »ç¿ë °¡´ÉÇÏ°í, ½Å·ÚÇÒ ¸¸ÇÑ ¹æ¹ýÀÌ µÉ ¼ö ÀÖÀ» °ÍÀÌ´Ù.

The aim of this study was to evaluate QLF (quantitative light-induced fluorescence) technology for the caries detection in primary teeth and validate the relationships between the cavity volume of carious lesions and QLF analysis results.
Total 125 tooth surfaces include 53 occlusal surfaces, and 72 proximal surfaces were investigated with the portable QLF device for detection of dental caries in primary molars. Micro-CT radiograph was also performed to classify carious lesions and calculate the cavity volume. QLF showed good accuracy and reliability (sensitivity 0.75 - 0.94, specificity 0.82 - 0.95, and AUROC 0.88 - 0.98) for the caries detection in primary teeth except ¥ÄR average results of proximal caries which showed relatively low values. Statistically significant relationships were found between ¥ÄF average, QS-Index and the cavity volume according to Spearman rank-order correlation coefficients (r = 0.805 - 0.832, p < 0.001). QLF detection method would be a harmless and reliable way for children to diagnose dental caries without the concern about radiation exposure.

Å°¿öµå

Dental carie;, Diagnosis; Primary teeth; Quantitative light-induced fluorescence; Micro-CT; Radiography

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